Biomedical applications of vibrational spectroscopy: Oral cancer diagnostics

Specific Applications of Vibrational Spectroscopy in Biomedical Engineering

Sylwia Olsztyńska-Janus1, Marlena Gąsior-Głogowska1,4, Katarzyna Szymborska-Małek2, Bogusława Czarnik-Matusewicz3 and Małgorzata Komorowska1,4 1Institute of Biomedical Engineering and Instrumentation, Wrocław University of Technology, 2Institute of Physical and Theoretical Chemistry, Wrocław University of Technology, 3Faculty of Chemistry, University of Wrocław, 4Regional Specialist Hospital in...

Biological and biomedical applications of two-dimensional vibrational spectroscopy: proteomics, imaging, and structural analysis.

In the last 10 years, several forms of two-dimensional infrared (2DIR) spectroscopy have been developed, such as IR pump-probe spectroscopy and photon-echo techniques. In this Account, we describe a doubly vibrationally enhanced four-wave mixing method, in which a third-order nonlinear signal is generated from the interaction of two independently tunable IR beams and an electron-polarizing visi...

The evolution of biomedical vibrational spectroscopy: A personal perspective

When my colleague Parvez Haris asked me to write a historical review on the evolution of biomedical vibrational spectroscopy I consented, but now I need to clarify what this review is about and what it is not. It is my personal belief that biomedical vibrational spectroscopy has yet to reach its full potential and therefore I will not restrict myself to recounting its past history but will look...

Salivary Diagnostics in Oral Cancer

Saliva is considered a mirror of body health and is composed of variety of analytes from systemic sources that reach the oral cavity through various pathways. Because water is a major constituent, saliva plays a key role in the lubrication and repair of oral mucosa, formation and swallowing of food bolus, digestion of starch, facilitation of food tasting and control of oropharyngeal microbial p...

Applications of Vibrational Spectroscopy in Criminal Forensic Analysis